SURFACTANT SYSTEM DYSFUNCTION AND PULMONARY BLOOD FLOW. † 2046
نویسندگان
چکیده
منابع مشابه
Surfactant and Pulmonary Blood Flow
Prematurely delivered lambs were treated with radiolabeled natural surfactant by either tracheal instillation at birth and before the onset of mechanical ventilation, or after 23±1 (±SE) min of mechanical ventilation. Right ventricular blood flow distributions, left ventricular outputs, and left-to-right ductal shunts were measured with radiolabeled microspheres. After sacrifice, the lungs of l...
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Explicit results concerning blood flow, alveolar blood volume, regional differences, and transit time distribution are derived from the sheet-flow theory and compared with experimental evidence available in the literature. A general consistency is indicated. The theory exhibits in a simple form the effects on flow of the arterial, alveolar, and venous pressures, the alveolar area, the mean path...
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unteers were studied, nine sitting and seven supine. During hypoxia there was a slight but significant increase in relative perfusion of the upper portions of the lungs in both the sitting and supine subjects. During recovery from hypoxia, blood flow distribution differed significantly from the control. The erect subjects showed increased relative perfusion of the lung bases and the supine subj...
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Increased airway resistance in asthma may be partly due to poor function of pulmonary surfactant. This study investigated the inflammatory changes of bronchoalveolar lavage fluid (BALF) and the performance of BALF surfactant in healthy control subjects (n = 9) and patients with mild allergic asthma (n = 15) before and after segmental challenge. BALF was obtained for baseline values, and 24 h af...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1996
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199604001-02070